Overview
Semaglutide is a GLP-1 receptor agonist that mimics the incretin hormone GLP-1, which is released after eating. It's one of the most effective peptides for weight loss and blood sugar control, FDA-approved for diabetes and obesity treatment.
How It Works
Semaglutide activates GLP-1 receptors in the brain to reduce appetite and increase satiety. It slows gastric emptying, reduces glucagon secretion, and enhances glucose-dependent insulin release from the pancreas.
Research Status
FDA approved for Type 2 diabetes (Ozempic) and chronic weight management (Wegovy). Extensive clinical trials showing efficacy.
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AOD-9604
AOD-9604 is a synthetic 16-amino acid peptide fragment derived from the C-terminal portion of human growth hormone (amino acids 176-191). It was developed to harness growth hormone's lipolytic (fat-burning) properties without affecting blood sugar or growth.
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Tesamorelin is a synthetic 44-amino acid GHRH (Growth Hormone Releasing Hormone) analog with enhanced stability. It is the only FDA-approved peptide for reducing visceral adipose tissue, originally developed for HIV-associated lipodystrophy.