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AOD-9604

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Also known as: Anti-Obesity Drug 9604, HGH Fragment 176-191

Overview

AOD-9604 is a synthetic 16-amino acid peptide fragment derived from the C-terminal portion of human growth hormone (amino acids 176-191). It was developed to harness growth hormone's lipolytic (fat-burning) properties without affecting blood sugar or growth.

How It Works

AOD-9604 stimulates beta-3 adrenergic receptors in adipose tissue to break down stored fat. Unlike full HGH, it does not bind to growth hormone receptors responsible for IGF-1 secretion, avoiding growth-related side effects like acromegaly or insulin resistance.

Research Status

Phase 2/3 clinical trials completed. Development discontinued in 2007 due to modest results without lifestyle intervention. Available for research.