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Enclomiphene

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Also known as: Androxal, Trans-clomiphene

Overview

Enclomiphene is the active isomer of clomiphene that selectively blocks estrogen receptors in the hypothalamus, stimulating natural testosterone production without the side effects of the zuclomiphene isomer.

How It Works

Enclomiphene blocks estrogen receptors in the hypothalamus, reducing negative feedback and increasing GnRH, LH, and FSH release. This stimulates the testes to produce more testosterone naturally.

Research Status

Was in FDA approval process. Widely used in men's health clinics. Preferred SERM for testosterone optimization.